Invention Grant
- Patent Title: Multiple-pulse pumping for enhanced fluorescence detection and molecular imaging in cells and tissue
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Application No.: US14322998Application Date: 2014-07-03
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Publication No.: US09612245B2Publication Date: 2017-04-04
- Inventor: Ryan M. Rich , Ignacy Gryczynski , Julian Borejdo , Zygmunt Gryczynski
- Applicant: University of North Texas Health Science Center , Texas Christian University
- Applicant Address: US TX Fort Worth US TX Fort Worth
- Assignee: University of North Texas Health Science Center at Fort Worth,Texas Christian University
- Current Assignee: University of North Texas Health Science Center at Fort Worth,Texas Christian University
- Current Assignee Address: US TX Fort Worth US TX Fort Worth
- Agency: Chalker Flores, LLP
- Agent Edwin S. Flores
- Main IPC: G01N21/64
- IPC: G01N21/64 ; G01N33/58
Abstract:
The present invention includes a method and system for enhancing the signal-to-noise ratio in emission detection comprising: selecting a probe capable of at least one of fluorescence, phosphorescence, or delayed fluorescence in or about a sample that comprises interfering background signal; and exposing the probe to one or more controllable bursts, each burst comprising two or more pulses, wherein the one or more controllable bursts of high repetition energy pulses enhance the signal from the probe above that of the background signal.
Public/Granted literature
- US20150011406A1 MULTIPLE-PULSE PUMPING FOR ENHANCED FLUORESCENCE DETECTION AND MOLECULAR IMAGING IN CELLS AND TISSUE Public/Granted day:2015-01-08
Information query
