An electro-optic assembly is provided that includes a first substantially transparent substrate comprising: a first surface, and a second surface. The second surface comprises a first electrically conductive layer and a first isolation area. The assembly further includes a second substrate comprising: a third surface, and a fourth surface. The third surface comprises a second electrically conductive layer. The assembly also includes a primary seal between the second and third surfaces, the seal and the second and third surfaces define a substantially hermetic cavity; and an electro-optic medium at least partially disposed in the cavity. The primary seal comprises a plurality of conductive spacers, the seal disposed in contact with portions of the first and second electrically conductive layers. A substantial portion of the plurality of conductive spacers is in substantial contact with the second and third surfaces.