An adaptive power-switch circuit suitable for an electronic device includes a multi-gate power switch module, a monitoring module and a driving controller circuit. The multi-gate power switch module includes to plurality of power switch units connected in parallel. The power switch units include a gate control terminal respectively. The monitoring module is used to monitor an operating load of the electronic device. The driving control circuit is coupled to the monitoring module to selectively disable the gate controlling terminals to form a plurality of configurations. The driving control circuit selects one of the configurations to operate the multi-gate power switch module according to the operating load.