Invention Grant
- Patent Title: Use of MicroRNA or inhibitors thereof in regulation of lipid metabolism
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Application No.: US14763902Application Date: 2014-01-26
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Publication No.: US09616086B2Publication Date: 2017-04-11
- Inventor: Bin Hong , Li Wang , Xiaojian Jia , Huajun Jiang , Yu Du , Fan Yang , Shuyi Si
- Applicant: Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences
- Applicant Address: CN Beijing
- Assignee: Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences
- Current Assignee: Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences
- Current Assignee Address: CN Beijing
- Agency: Sterne, Kessler, Goldstein & Fox P.L.L.C.
- Priority: CN201310035358 20130130
- International Application: PCT/CN2014/071485 WO 20140126
- International Announcement: WO2014/117697 WO 20140807
- Main IPC: C12N15/11
- IPC: C12N15/11 ; A61K31/713 ; C12Q1/68 ; A61K31/7105 ; C12N15/113 ; G01N33/92
Abstract:
The present invention relates to use of a microRNA or an inhibitor thereof, and specifically, the present invention relates to use of a microRNA or an inhibitor thereof in preparing a medicament for regulating lipid metabolism or preparing a medicament for preventing or treating a disease related to lipid metabolism. The microRNA is one or more of the following: miRNA-96, miRNA-185, and miRNA-223. The present invention also relates to use of the microRNA or the inhibitor thereof in regulating the expression level of a protein related to lipid metabolism. The present invention also relates to a composition comprising the microRNA or the inhibitor thereof. The microRNA or the inhibitor thereof in the present invention can be used as a pharmaceutical component, and can be applied in preventing or treating a disease caused by lipid metabolism disorders such as hyperlipidemia, atherosclerosis, coronary heart disease or other diseases.
Public/Granted literature
- US20160089390A1 Use of MicroRNA or Inhibitors Thereof in Regulation of Lipid Metabolism Public/Granted day:2016-03-31
Information query
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