Invention Grant
- Patent Title: Use of fluorinated derivatives of 4-aminopyridine in therapeutics and medical imaging
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Application No.: US14329597Application Date: 2014-07-11
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Publication No.: US09617215B2Publication Date: 2017-04-11
- Inventor: Pedro Brugarolas , Brian Popko , Daniel Appelbaum , Chin-Tu Chen
- Applicant: THE UNIVERSITY OF CHICAGO
- Applicant Address: US IL Chicago
- Assignee: THE UNIVERSITY OF CHICAGO
- Current Assignee: THE UNIVERSITY OF CHICAGO
- Current Assignee Address: US IL Chicago
- Agency: Norton Rose Fulbright US LLP
- Main IPC: A61M36/14
- IPC: A61M36/14 ; A61K51/00 ; C07D213/73 ; A61K51/04 ; C07D213/75 ; C07B59/00

Abstract:
The present disclosure provides novel compounds, including compounds that bind to potassium channels, methods for their manufacture, and methods for their use, including their use to diagnose and/or assess traumatic brain injury and use to treat dymeylinating diseases, and/or in vivo imaging of the central nervous system, and to diagnose and/or assess the progression of MS or other diseases.
Public/Granted literature
- US20140369932A1 USE OF FLUORINATED DERIVATIVES OF 4-AMINOPYRIDINE IN THERAPEUTICS AND MEDICAL IMAGING Public/Granted day:2014-12-18
Information query