Invention Grant
- Patent Title: Indanylaminopyridylcyclopropanecarboxylic acids, pharmaceutical compositions and uses thereof
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Application No.: US15225038Application Date: 2016-08-01
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Publication No.: US09617251B2Publication Date: 2017-04-11
- Inventor: Matthias Eckhardt , Stefan Peters , Holger Wagner
- Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GMBH
- Applicant Address: DE Ingelheim am Rhein
- Assignee: Boehringer Ingelheim International GmbH
- Current Assignee: Boehringer Ingelheim International GmbH
- Current Assignee Address: DE Ingelheim am Rhein
- Agent Michael P. Morris; David L. Kershner
- Priority: EP15180175 20150807; EP15199739 20151214
- Main IPC: C07D413/12
- IPC: C07D413/12 ; C07D401/12 ; A61K31/4439 ; A61K45/06 ; C07D213/74 ; A61K31/4418 ; C07D405/12 ; A61K31/443 ; A61K31/4433 ; A61K31/4427 ; A61K31/444 ; A61K31/497 ; A61K31/513 ; C07D409/12 ; A61K31/4436

Abstract:
The present invention relates to compounds of general formula I, wherein the groups R, R1, R2, R3, m and n are defined as in claim 1, which have valuable pharmacological properties, in particular bind to the GPR40 receptor and modulate its activity. The compounds are suitable for treatment and prevention of diseases which can be influenced by this receptor, such as metabolic diseases, in particular diabetes type 2. Furthermore, the invention relates to novel intermediates, useful for the synthesis of compounds of formula I.
Public/Granted literature
- US20170037040A1 INDANYLAMINOPYRIDYLCYCLOPROPANECARBOXYLIC ACIDS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF Public/Granted day:2017-02-09
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