- Patent Title: Mutated organophosphorus acid anhydrolases and their uses thereof
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Application No.: US14946204Application Date: 2015-11-19
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Publication No.: US09617526B1Publication Date: 2017-04-11
- Inventor: Steven P. Harvey , Mark A. Guelta
- Applicant: U.S. Army Edgewood Chemical and Biological Command
- Applicant Address: US DC Washington
- Assignee: The United States of America as represented by the Secretary of the Army
- Current Assignee: The United States of America as represented by the Secretary of the Army
- Current Assignee Address: US DC Washington
- Agent Ulysses John Biffoni
- Main IPC: D06M16/00
- IPC: D06M16/00 ; C02F3/34 ; B09C1/10 ; C12N9/14 ; C12P21/06 ; C12P19/34 ; A62D3/34 ; C07H21/04 ; C07K1/00 ; C12N9/16 ; A61K38/46
Abstract:
The invention is directed toward non-wild-type organophosphorus acid anhydrolases having three site mutations, method of production, and method of use to effectively degrade toxic chemical compounds such as (Ethyl({2-[bis(propan-2-yl)amino]ethyl}sulfanyl)(methyl)phosphinate (“VX”).
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