An air-conditioning system integrated with an application program (APP) of a smart portable device comprises at least an air-conditioning controller, an APP and a plurality of air-conditioning devices. The air-conditioning controller comprises a temperature sensor, provided for sensing an environment temperature so as to transmit a temperature signal. The APP is installed on a smart portable device such that the APP can transmit an operation signal to the air-conditioning controller according to the temperature signal via the smart portable device. The air-conditioning controller further transmits a control signal to the plurality of air-conditioning devices such that the air-conditioning devices can be operated according to the control signal.