Methods and systems for analyzing bus traffic in a target device, such as a system on-a-chip (SOC) comprises capturing a processor event and generating an interrupt based on a threshold associated with the processor event. Based on at least the interrupt, a instruction pointer associated with the processor event that generated the interrupt is identified. An instruction analyzer identifies a memory address of the instruction associated with the processor event that generated the interrupt. At least the processor event and a associated instruction information are collected by a sample collector and transferred to a host for performance profiling.