Described is a memory searching system, including an indexing module and a searching module. The indexing module, provided with multiple indexed databases, acquires and records updated indexed data in an indexed database provided to the indexing module and synchronizes the searching module with the updated indexed data recorded in the indexed database provided to the indexing module. The searching module updates an indexed database in a memory with the updated indexed data received from the indexing module (the indexed database in the memory corresponds to the indexed database provided to the indexing module), and switches a pointer of the indexed database to the updated indexed database in the memory. Also described is a memory searching method, a real-time searching system and method, capable of better supporting real-time search and of updating indexed data in seconds in a realistic application, reducing the cost of hardware equipment and improving searching efficiency.