Wettability of positive and negative electrode active material layers is improved by having the ratio of the liquid absorption speed of an electrolyte to the positive and negative electrode active material layers in an appropriate range when an aqueous binder is used in the negative electrode active material layer. The non-aqueous electrolyte secondary battery has a power generating element having a positive electrode active material layer on a surface of a positive electrode current collector, a negative electrode active material layer containing an aqueous binder on a surface of a negative electrode current collector, and a separator, and Tc/Ta is in the range of 0.6 to 1.3 when Tc is the soak-in time of the electrolyte liquid into the positive electrode active material layer and Ta is the soak-in time of the electrolyte liquid into the negative electrode active material layer.