Invention Grant
- Patent Title: Quinolinone five-membered heterocyclic compounds as mutant-isocitrate dehydrogenase inhibitors
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Application No.: US14858153Application Date: 2015-09-18
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Publication No.: US09624216B2Publication Date: 2017-04-18
- Inventor: Jian Lin , Anna Ericsson , Ann-Marie Campbell , Gary Gustafson , Zhongguo Wang , R. Bruce Diebold , Susan Ashwell , David R. Lancia, Jr. , Justin Andrew Caravella , Wei Lu
- Applicant: Forma Therapeutics, Inc.
- Applicant Address: US MA Watertown
- Assignee: FORMA THERAPEUTICS, INC.
- Current Assignee: FORMA THERAPEUTICS, INC.
- Current Assignee Address: US MA Watertown
- Agency: Cooley LLP
- Main IPC: C07D417/12
- IPC: C07D417/12 ; C07D471/04 ; C07D417/14
Abstract:
The invention relates to inhibitors of mutant isocitrate dehydrogenase (mt-IDH) proteins with neomorphic activity useful in the treatment of cell-proliferation disorders and cancers, having the Formula: where Y1, X1, X2, Y2, W1, W2, W3, and R1-R5 are described herein.
Public/Granted literature
- US20160311818A1 QUINOLINONE FIVE-MEMBERED HETEROCYCLIC COMPOUNDS AS MUTANT-ISOCITRATE DEHYDROGENASE INHIBITORS Public/Granted day:2016-10-27
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