Invention Grant
- Patent Title: Antibodies which bind to epithelial membrane protein 2 (EMP2)
-
Application No.: US14666091Application Date: 2015-03-23
-
Publication No.: US09624304B2Publication Date: 2017-04-18
- Inventor: Jonathan Braun , Lynn K. Gordon , Kaori Shimazaki Dadgostar , Madhuri Wadehra , Kathy A. Kelly , Anna M. Wu
- Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
- Applicant Address: US CA Oakland
- Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
- Current Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
- Current Assignee Address: US CA Oakland
- Agency: Morgan, Lewis & Bockius LLP
- Agent Jeffry S. Mann
- Main IPC: A61K39/395
- IPC: A61K39/395 ; C07K16/30 ; C07K16/12 ; C07K16/28 ; A61K45/06
Abstract:
The present invention provides methods and compositions useful in the treatment or prevention of Chlamydia infections and cancer. The methods and compositions inhibit the entry of Chlamydia into a host cell expressing EMP2 by interfering with the interaction between the Chlamydia and EMP2. The methods and compositions target cancers which express or overexpress EMP2 nucleic acids and polypeptides by targeting EMP2.
Public/Granted literature
- US20150329641A1 EMP2 ANTIBODIES AND THEIR THERAPEUTIC USES Public/Granted day:2015-11-19
Information query
