Invention Grant
- Patent Title: Modulation of apolipoprotein C-III expression
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Application No.: US15143222Application Date: 2016-04-29
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Publication No.: US09624496B2Publication Date: 2017-04-18
- Inventor: Rosanne M. Crooke , Mark J. Graham , Kenneth W. Dobie
- Applicant: Ionis Pharmaceuticals, Inc.
- Applicant Address: US CA Carlsbad
- Assignee: Ionis Pharmaceuticals, Inc.
- Current Assignee: Ionis Pharmaceuticals, Inc.
- Current Assignee Address: US CA Carlsbad
- Agency: Ionis Pharmaceuticals, Inc. Patent Dept.
- Main IPC: C12N15/11
- IPC: C12N15/11 ; A61K48/00 ; C12N15/113 ; A61K38/00
Abstract:
Compounds, compositions and methods are provided for modulating the expression of apolipoprotein C-III. The compositions comprise oligonucleotides, targeted to nucleic acid encoding apolipoprotein C-III. Methods of using these compounds for modulation of apolipoprotein C-III expression and for diagnosis and treatment of disease associated with expression of apolipoprotein C-III are provided.
Public/Granted literature
- US20160237434A1 MODULATION OF APOLIPOPROTEIN C-III EXPRESSION Public/Granted day:2016-08-18
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