Example systems and methods for configuring media devices utilizing audio codes and/or signatures are disclosed. Example methods disclosed herein include determining a characteristic of audio data received by a device, the characteristic including at least one of a code detected in the audio data or a signature generated from the audio data. Disclosed example methods also include determining whether the characteristic is mapped to at least one of a first command or a second command. Disclosed example methods further include, in response to determining the characteristic is mapped to the first command, executing the first command to cause the device to connect to a communication session to receive an upgrade to software executable on the device, and in response to determining the characteristic is mapped to the second command, executing the second command to cause a previously locked feature of the device to be unlocked.