Invention Grant
- Patent Title: Tamper resistant dosage form comprising an anionic polymer
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Application No.: US13223384Application Date: 2011-09-01
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Publication No.: US09636303B2Publication Date: 2017-05-02
- Inventor: Lutz Barnscheid , Sebastian Schwier , Johannes Bartholomäus
- Applicant: Lutz Barnscheid , Sebastian Schwier , Johannes Bartholomäus
- Applicant Address: DE Aachen
- Assignee: GRUENENTHAL GMBH
- Current Assignee: GRUENENTHAL GMBH
- Current Assignee Address: DE Aachen
- Agency: Norris McLaughlin & Marcus, P.A.
- Priority: EP10009125 20100902
- Main IPC: A61K31/485
- IPC: A61K31/485 ; A61K31/135 ; A61P25/04 ; A61K47/34 ; A61K9/20 ; A61K31/137

Abstract:
A pharmaceutical dosage form and method of using same, the pharmaceutical dosage form exhibiting a breaking strength of at least 500 N, said dosage form containing a pharmacologically active ingredient (A); a physiologically acceptable polymer (B) obtainable by polymerization of a monomer composition comprising an ethylenically unsaturated monomer bearing an anionic functional group, in protonated form or a physiologically acceptable salt thereof; a polyalkylene oxide (C) having a weight average molecular weight of at least 200,000 g/mol, wherein the content of the polyalkylene oxide (C) is at least 20 wt.-%, based on the total weight of the dosage form; wherein the pharmacologically active ingredient (A) is present in a controlled-release matrix comprising the polymer (B) and the polyalkylene oxide (C).
Public/Granted literature
- US20120065220A1 Tamper Resistant Dosage Form Comprising An Anionic Polymer Public/Granted day:2012-03-15
Information query
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