Invention Grant
- Patent Title: Substituted bicyclic compounds as bromodomain inhibitors
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Application No.: US14900138Application Date: 2014-06-20
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Publication No.: US09636328B2Publication Date: 2017-05-02
- Inventor: Shuang Liu , John Frederick Quinn , Bryan Cordell Duffy , Ruifang Wang , May Xiaowu Jiang , Gregory Scott Martin , He Zhao , Michael Ellis , Gregory Steven Wagner , Peter Ronald Young
- Applicant: ZENITH EPIGENETICS CORP.
- Applicant Address: CA Calgary, AB
- Assignee: Zenith Epigenetics Ltd.
- Current Assignee: Zenith Epigenetics Ltd.
- Current Assignee Address: CA Calgary, AB
- Agency: Finnegan, Henderson, Farabow, Garrett & Dunner, LLP
- International Application: PCT/IB2014/002240 WO 20140620
- International Announcement: WO2015/004534 WO 20150115
- Main IPC: C07D235/26
- IPC: C07D235/26 ; A61K31/4184 ; C07D405/14 ; C07D403/14 ; C07D405/04 ; C07D417/14 ; C07D471/04 ; A61K31/422 ; A61K31/423 ; A61K31/427 ; A61K31/4439 ; A61K31/4709 ; A61K45/06 ; C07D413/04 ; C07D413/14 ; A61K31/426 ; A61K31/428 ; A61K31/437 ; A61K31/4725 ; A61K31/496 ; A61K31/497 ; A61K31/4985 ; A61K31/501 ; A61K31/506 ; A61K31/517 ; A61K31/5377 ; A61K31/538 ; C07D409/14 ; C07D487/04
Abstract:
The invention relates to substituted bicyclic compounds, which are useful for inhibition of BET protein function by binding to bromodomains, pharmaceutical compositions comprising these compounds, and use of the compounds and compositions in therapy.
Public/Granted literature
- US20160145248A1 NOVEL SUBSTITUTED BICYCLIC COMPOUNDS AS BROMODOMAIN INHIBITORS Public/Granted day:2016-05-26
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