Embodiments of the present disclosure relate generally to inflation systems. Specific embodiments relate to inflation systems that use a mixed flow compressor to deliver a diagonal airflow for inflation. The inflation systems disclosed do not require the use of compressed gas, but can use a battery-powered or otherwise electric motor for generating airflow from ambient air. Particular embodiments may find use in connection with inflating evacuation slides or life rafts on board a passenger transportation vehicle, such as an aircraft or marine vessel. Other embodiments may be used for inflating shelters, life vests, or any other safety device that requires a rapid inflation.