Invention Grant
- Patent Title: Salt forms of [R-(R*,R*)]-2-(4-fluorophenyl)-β, δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic-acid
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Application No.: US15061931Application Date: 2016-03-04
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Publication No.: US09637449B2Publication Date: 2017-05-02
- Inventor: Joseph Francis Krzyzaniak , Jason Albert Leonard
- Applicant: Pfizer Inc.
- Applicant Address: US NY New York
- Assignee: Pfizer Inc.
- Current Assignee: Pfizer Inc.
- Current Assignee Address: US NY New York
- Agent Francis J. Tinney
- Main IPC: C07D207/34
- IPC: C07D207/34 ; C07D295/037 ; C07C211/07 ; C07C215/08 ; C07C229/26 ; C07D295/027
![Salt forms of [R-(R*,R*)]-2-(4-fluorophenyl)-β, δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic-acid](/abs-image/US/2017/05/02/US09637449B2/abs.jpg.150x150.jpg)
Abstract:
Novel salt forms of [R—(R*,R*)]-2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic acid characterized by their X-ray powder diffraction pattern and solid-state NMR spectra are described, as well as methods for the preparation and pharmaceutical composition of the same, which are useful as agents for treating hyperlipidemia, hypercholesterolemia, osteoporosis, benign prostatic hyperplasia, and Alzheimer's Disease.
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