Invention Grant
- Patent Title: 2,3-disubstituted 1-acyl-4-amino-1,2,3,4-tetrahydroquinoline derivatives and their use as bromodomain inhibitors
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Application No.: US14770499Application Date: 2014-03-12
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Publication No.: US09637456B2Publication Date: 2017-05-02
- Inventor: Dominique Amans , Stephen John Atkinson , Lee Andrew Harrison , David Jonathan Hirst , Robert Peter Law , Matthew Lindon , Alexander Preston , Jonathan Thomas Seal , Christopher Roland Wellaway
- Applicant: GlakoSmithKline Intellectual Property (No. 2) Limited
- Applicant Address: GB Brentford, Middlesex
- Assignee: GlaxoSmithKline Intellectual Property (No. 2) Limited
- Current Assignee: GlaxoSmithKline Intellectual Property (No. 2) Limited
- Current Assignee Address: GB Brentford, Middlesex
- Agent Duke M. Fitch; Kathryn A. Lutomski; Edward R. Gimmi
- International Application: PCT/EP2014/054795 WO 20140312
- International Announcement: WO2014/140076 WO 20140918
- Main IPC: C07D215/44
- IPC: C07D215/44 ; C07D401/12 ; A61K31/4709 ; A61K31/506 ; C07D401/14 ; C07D405/14 ; C07D413/14 ; C07D215/227 ; C07D215/46 ; C07D215/48 ; C07D401/04 ; C07D405/04 ; C07D409/12 ; C07D409/14 ; C07D413/04 ; C07D413/12 ; C07D417/12 ; C07D417/14 ; C07D471/04 ; C07D471/08 ; C07D487/08 ; C07D498/04 ; A61K31/4375 ; A61K31/4706 ; A61K31/496 ; A61K31/497 ; A61K31/5377 ; A61K31/5386 ; C07D498/08
Abstract:
The present invention relates to novel compounds, pharmaceutical compositions containing such compounds and to their use in therapy.
Public/Granted literature
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