Invention Grant
- Patent Title: 3′ Equatorial-fluorine-substituted neuraminidase inhibitor compounds, compositions and methods for the use thereof as anti-virals
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Application No.: US14372820Application Date: 2013-01-17
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Publication No.: US09637465B2Publication Date: 2017-05-02
- Inventor: Stephen Withers , Hongming Chen , Ricardo Resende , Jennifer Lois Breschkin
- Applicant: THE UNIVERSITY OF BRITISH COLUMBIA
- Applicant Address: CA Vancouver
- Assignee: The University of British Columbia
- Current Assignee: The University of British Columbia
- Current Assignee Address: CA Vancouver
- Agency: Bozicevic, Field & Francis LLP
- Agent Rudy J. Ng; Carol L. Francis
- International Application: PCT/CA2013/050034 WO 20130117
- International Announcement: WO2013/106937 WO 20130725
- Main IPC: A61K31/35
- IPC: A61K31/35 ; C07D309/00 ; C07D309/14
Abstract:
Equatorial 2,3-fluorinated glycosides compounds of formula (I) useful for the treatment or prophylaxis of viral infection, particularly viral influenza, the methods for their preparation, and their pharmaceutical compositions. The therapeutic effect is achieved via inhibition of viral neuraminidases.
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