Invention Grant
- Patent Title: Acrylamide derivatives as antimalarial agents
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Application No.: US14777459Application Date: 2014-03-14
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Publication No.: US09637473B2Publication Date: 2017-05-02
- Inventor: Hamed Aissaoui , Christoph Boss , Claire-Lise Ciana , Thierry Kimmerlin , Romain Siegrist
- Applicant: Actelion Pharmaceuticals Ltd
- Applicant Address: CH Allschwil
- Assignee: ACTELION PHARMACEUTICALS LTD.
- Current Assignee: ACTELION PHARMACEUTICALS LTD.
- Current Assignee Address: CH Allschwil
- Agency: Hoxie & Associates LLC
- Priority: EP13159422 20130315
- International Application: PCT/IB2014/059801 WO 20140314
- International Announcement: WO2014/141175 WO 20140918
- Main IPC: C07D401/12
- IPC: C07D401/12 ; C07D471/04 ; C07D417/14 ; C07D413/14 ; C07D401/14 ; C07D403/12 ; C07D213/75 ; C07D211/58

Abstract:
The invention relates to novel acrylamide derivatives of the formula I wherein R1, R2, R3, X, and ring A are as defined in the description, and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including pharmaceutical compositions containing those compounds and their use as medicaments for the treatment or prevention of protozoal infections, such as especially malaria.
Public/Granted literature
- US20160024050A1 NOVEL ACRYLAMIDE DERIVATIVES AS ANTIMALARIAL AGENTS Public/Granted day:2016-01-28
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