Invention Grant
- Patent Title: Dominant negative mutant KRP protein protection of active cyclin-CDK complex inhibition by wild-type KRP
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Application No.: US14253004Application Date: 2014-04-15
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Publication No.: US09637754B2Publication Date: 2017-05-02
- Inventor: Paul Olivier , Jay Derocher , James Roberts
- Applicant: TARGETED GROWTH, INC.
- Applicant Address: US WA Burien
- Assignee: Targeted Growth, Inc.
- Current Assignee: Targeted Growth, Inc.
- Current Assignee Address: US WA Burien
- Main IPC: C12N15/82
- IPC: C12N15/82 ; C07K14/415 ; C12N9/12
Abstract:
Disclosed are mutant CDK inhibitor (CKI) polypeptides having dominant negative antagonist activity against wild-type CKI proteins, as well as related compositions, including nucleic acids and vectors encoding the mutant CKI polypeptides and transformed host cells and transgenic plants comprising such nucleic acids and vectors. Also disclosed are related methods for using the mutant proteins to modulate cell division in cells, particularly plant cells.
Public/Granted literature
- US20140331362A1 DOMINANT NEGATIVE MUTANT KRP PROTEIN PROTECTION OF ACTIVE CYCLIN-CDK COMPLEX INHIBITION BY WILD-TYPE KRP Public/Granted day:2014-11-06
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