Invention Grant
- Patent Title: Host cells and methods for producing 1-deoxyxylulose 5-phosphate (DXP) and/or a DXP derived compound
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Application No.: US15186202Application Date: 2016-06-17
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Publication No.: US09637766B2Publication Date: 2017-05-02
- Inventor: James Kirby , Jeffrey L. Fortman , Minobu Nishimoto , Jay D. Keasling
- Applicant: The Regents of the University of California
- Applicant Address: US CA Oakland
- Assignee: The Regents of the University of California
- Current Assignee: The Regents of the University of California
- Current Assignee Address: US CA Oakland
- Agency: Lawrence Berkeley National Laboratory
- Agent Robin C. Chiang
- Main IPC: C12P5/00
- IPC: C12P5/00 ; C12P19/02 ; C12N9/04
Abstract:
The present invention provides for a genetically modified host cell capable of producing 1-deoxyxylulose 5-phosphate or 1-deoxy-D-xylulose 5-phosphate (DXP) (12), and optionally one or more DXP derived compounds, comprising: (a) a mutant RibB, or functional variant thereof, capable of catalyzing xylulose 5-phoshpate and/or ribulose 5-phospate to DXP, or (b) a YajO, or functional variant thereof, and a XylB, or functional variant thereof.
Public/Granted literature
- US20160298153A1 Host Cells and Methods for Producing 1-Deoxyxylulose 5-phosphate (DXP) and/or a DXP Derived Compound Public/Granted day:2016-10-13
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