Invention Grant
- Patent Title: Digital sequence analysis of DNA methylation
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Application No.: US13364978Application Date: 2012-02-02
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Publication No.: US09637792B2Publication Date: 2017-05-02
- Inventor: David A. Ahlquist , William R. Taylor , Hongzhi Zou , Graham P. Lidgard
- Applicant: David A. Ahlquist , William R. Taylor , Hongzhi Zou , Graham P. Lidgard
- Applicant Address: US MN Rochester US WI Madison
- Assignee: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH,EXACT SCIENCES CORPORATION
- Current Assignee: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH,EXACT SCIENCES CORPORATION
- Current Assignee Address: US MN Rochester US WI Madison
- Agency: Casimir Jones, S.C.
- Agent Mary Ann Brow
- Main IPC: C12Q1/68
- IPC: C12Q1/68
Abstract:
The present invention relates to methods and compositions for determination of and uses of specific methylation patterns indicative of adenoma and carcinoma. In particular, the invention relates to analysis of defined CpG loci that are coordinately methylated in DNAs from cancer and adenoma samples, methods for identifying coordinately methylated loci, and methods of using analysis of coordinately methylated loci in one or more marker regions in the design of assays for adenoma and cancer.
Public/Granted literature
- US20120196756A1 DIGITAL SEQUENCE ANALYSIS OF DNA METHYLATION Public/Granted day:2012-08-02
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