A hanging system for securing cladding panel on a building structure, the cladding panel having a mounting channel extending at least partly across a surface thereof. An embedded anchor block has a core and two engaging portions outwardly projecting from the core, the two engaging portions operable to lock the anchor block in the mounting channel of the cladding panel in an interlocking fit when the embedded anchor block is received within the mounting channel, and the embedded anchor block having an outer surface that is configured to be flush or near flush with the surface of the cladding panel when the embedded anchor block is received within the mounting channel. A hanging clip removably connects or fastens to the anchor block, the hanging clip having an engagement surface to engage the outer surface of the anchor block. The cladding panel is secured to a building structure by fastening the anchor block to the hanging clip which is securable to a support.