Invention Grant
- Patent Title: Biomarkers of oxidative stress
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Application No.: US14069913Application Date: 2013-11-01
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Publication No.: US09638699B2Publication Date: 2017-05-02
- Inventor: Gemma Alexandra Figtree , Chia-Chi Liu , Natasha Alexandria Sarah Fry , Keyvan Karimi Galougahi
- Applicant: Northern Sydney Local Health District , The University of Sydney
- Applicant Address: AU Sydney AU St. Leonards
- Assignee: The University of Sydney,Northern Sydney Local Health District
- Current Assignee: The University of Sydney,Northern Sydney Local Health District
- Current Assignee Address: AU Sydney AU St. Leonards
- Agency: Casimir Jones, SC
- Priority: AU2013902669 20130718
- Main IPC: G01N33/68
- IPC: G01N33/68
Abstract:
The present invention relates to a method for detecting cardiovascular oxidative stress in an individual, comprising detecting in a blood sample from the individual modification of a cysteine at position 45 of the β1-subunit of the human erythrocyte ATP-dependent Na+K+ pump protein or of an equivalent cysteine in a homolog or variant thereof. The invention further relates to a kit for detecting cardiovascular oxidative stress in an individual, the kit comprising at least one agent for detecting the presence of a modification in a cysteine at position 45 of the β1-subunit of the human erythrocyte ATP-dependent Na+K+ pump protein or of an equivalent cysteine in a homolog or variant thereof, wherein said modification is a result of oxidation.
Public/Granted literature
- US20150024413A1 BIOMARKERS OF OXIDATIVE STRESS Public/Granted day:2015-01-22
Information query
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