Invention Grant
- Patent Title: Magnetic resonance imaging (MRI) with self-navigation and self-registration
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Application No.: US14177244Application Date: 2014-02-11
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Publication No.: US09640070B2Publication Date: 2017-05-02
- Inventor: Mark Griswold , Vikas Gulani , Greg Lee , Nicole Seiberlich
- Applicant: Case Western Reserve University
- Applicant Address: US OH Cleveland
- Assignee: Case Western Reserve University
- Current Assignee: Case Western Reserve University
- Current Assignee Address: US OH Cleveland
- Agency: Quarles & Brady LLP
- Main IPC: A61B5/05
- IPC: A61B5/05 ; G08C23/06 ; G01R33/36 ; G01R33/56 ; G01R33/48 ; G01R33/58 ; A61K49/06 ; A61B5/00 ; G01R33/563 ; A61B5/055

Abstract:
Three-dimensional (3D) projections of nuclear magnetic resonance (NMR) signals are acquired from a liver experiencing NMR in response to a 3D multi-echo non-Cartesian pulse sequence. The projections are reconstructed into two sets of images having different resolutions. Bins associated with the different positions to which the liver moves during respiration are identified in lower resolution images, and then higher resolution images are binned into the position dependent bins based on navigator data in the lower resolution images. A combined image for a bin is made from images located in the bin and then registered to a reference image. An overall combined image is made by summing the combined bin images. Quantized data for a contrast agent concentration in the liver is produced using signal intensity in the overall combined image. The quantized value may describe a liver perfusion parameter. A diagnosis may be made from the quantized value.
Public/Granted literature
- US20140296702A1 Magnetic Resonance Imaging (MRI) With Self-Navigation and Self-Registration Public/Granted day:2014-10-02
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