Physiological cues, such as elevated heart or respiratory rates can be masked from video of a person before the video is sent to another party. The masking of human-perceptible and non-human-perceptible physiological cues removes information from the video that another party could use to determine the person's emotional state. For example, variations in a person's skin color that are typically imperceptible to the human eye and from which a person's heart rate can be detected, can be removed or altered so that another party viewing the video cannot determine the person's actual heart rate in an attempt to determine the person's emotional state, even if they are performing computer analysis on the video. The presence of some physiological cues can be determined by detecting that a physiological measure is above a specified physiological measure threshold. Modified video can have the characteristic that physiological cues are substantially absent in the modified video or that physiological measures extracted from the modified video have a value below an associated physiological measure threshold.