A method and system for producing tomosynthesis images of a breast specimen in a cabinet x-ray system. An X-ray source delivers X-rays through a specimen of excised tissue and forms an image at a digital X-ray detector. Multiple X-ray images are taken as the X-ray source moves relative to the stationary breast specimen. In the preferred embodiment, the X-ray source moves in a range from about 350° to and including about 10°. The X-ray source may travel substantially along a path that generally defines an arc, or linearly, while the digital X-ray detector remains stationary throughout and the X-ray source remains substantially equidistant from the specimen platform. The set of X-ray image data taken at the different points are combined to form a tomosynthesis image that can be viewed in different formats, alone or as an adjunct to conventional specimen radiography.