Invention Grant
- Patent Title: Indolinone derivative as tyrosine kinase inhibitor
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Application No.: US14650270Application Date: 2013-12-06
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Publication No.: US09642851B2Publication Date: 2017-05-09
- Inventor: Hoyin Lo , Aichen Wang , Qian Zhang
- Applicant: KBP Biosciences Co., Ltd.
- Applicant Address: CN Jinan, Shandong Province
- Assignee: KBP BioSciences Co., Ltd.
- Current Assignee: KBP BioSciences Co., Ltd.
- Current Assignee Address: CN Jinan, Shandong Province
- Agency: Fitch, Even, Tabin & Flannery, LLP
- Priority: CN201210519315 20121206
- International Application: PCT/CN2013/001512 WO 20131206
- International Announcement: WO2014/086102 WO 20140612
- Main IPC: C07D209/14
- IPC: C07D209/14 ; C07D413/12 ; C07D413/14 ; C07D403/12 ; A61K31/4045 ; A61K31/407 ; A61K31/496 ; C07D405/14 ; C07D401/12 ; C07D405/12 ; C07D417/14 ; C07D209/34 ; A61K45/06 ; A61K31/5377 ; C07D409/14 ; C07D487/04 ; C07D498/04 ; C07D209/30 ; C07D401/14 ; A61K31/435 ; A61K31/438 ; A61K31/439 ; A61K31/4439 ; A61K31/4995 ; A61K31/506 ; C07D403/14 ; C07D471/10 ; C07D471/14 ; C07D487/08 ; C07D487/10 ; C07D491/107 ; A61K31/4155 ; A61K31/4196 ; A61K31/433 ; A61K31/454 ; A61K31/5383 ; C07D471/04 ; C07D405/04
Abstract:
The present invention relates to a compound represented by general formula (I), a method for preparing said compound, a pharmaceutical formulation containing said compound, and the use of said compound in manufacture of a medicament for treating or preventing the fibrous degeneration disease and treating the excessive proliferation disease: wherein ring A, X, R1, R2, R3, R4, R5, R6, R7, R8, R9, a, b and n are defined as those in the description.
Public/Granted literature
- US20150306095A1 An Indolinone Derivative As Tyrosine Kinase Inhibitor Public/Granted day:2015-10-29
Information query
