Invention Grant
- Patent Title: Cycloalkyl-dione derivatives and methods of their use
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Application No.: US14781424Application Date: 2014-04-03
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Publication No.: US09643919B2Publication Date: 2017-05-09
- Inventor: Carlo Ballatore , Kurt R. Brunden , Virginia M. Y. Lee , Amos B. Smith, III , John Q. Trojanowski , Xiaozhao Wang
- Applicant: The Trustees of The University of Pennsylvania
- Applicant Address: US PA Philadelphia
- Assignee: The Trustees Of The University Of Pennsylvania
- Current Assignee: The Trustees Of The University Of Pennsylvania
- Current Assignee Address: US PA Philadelphia
- Agency: Baker & Hostetler LLP
- International Application: PCT/US2014/032742 WO 20140403
- International Announcement: WO2014/165633 WO 20141009
- Main IPC: C07C311/20
- IPC: C07C311/20

Abstract:
The present invention is directed to compounds of formula I: wherein A is n is 0, 1, or 2; m is 0 or 1; R1 is H or C1-6alkyl and R2 is H, C1-6alkyl, C1-6alkaryl, aryl, or heteroaryl; and X is O or NH. Tautomers, enantiomers, and diastereomers, as well as pharmaceutically acceptable salt forms, of compounds of formula I are also within the scope of the invention. Methods of preparing and using the compounds of formula I are also described. wherein A is
Public/Granted literature
- US20160031805A1 CYCLOALKYL-DIONE DERIVATIVES AND METHODS OF THEIR USE Public/Granted day:2016-02-04
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