Invention Grant
- Patent Title: Compound having somatostatin receptor agonistic activity and pharmaceutical use thereof
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Application No.: US15025739Application Date: 2014-09-29
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Publication No.: US09643951B2Publication Date: 2017-05-09
- Inventor: Akiharu Ishida , Takeshi Matsushita , Tetsuya Sekiguchi , Yasuyuki Okabe , Tatsuya Komagata , Takuya Nishio
- Applicant: ONO PHARMACEUTICAL CO., LTD.
- Applicant Address: JP Osaka
- Assignee: ONO PHARMACEUTICAL CO., LTD.
- Current Assignee: ONO PHARMACEUTICAL CO., LTD.
- Current Assignee Address: JP Osaka
- Agency: Sughrue Mion, PLLC
- Priority: JP2013-205027 20130930; JP2013-268902 20131226
- International Application: PCT/JP2014/075794 WO 20140929
- International Announcement: WO2015/046482 WO 20150402
- Main IPC: C07D401/14
- IPC: C07D401/14 ; C07D498/04 ; A61K31/5383 ; A61K45/06 ; A61K31/4545 ; C07D401/04

Abstract:
The present invention provides a somatostatin receptor subtype 2 agonist. A disclosed compound represented by the general formula (I): wherein all symbols have the same definitions as described in the specification; a salt thereof, an N-oxide thereof or a solvate thereof, or a prodrug of the foregoing is a low-molecular compound having strong somatostatin receptor subtype 2 agonistic activity, and thus can be administered in a simple manner, has high stability and has low toxicity. Therefore, the present compound is useful for prophylaxis and/or therapy of somatostatin-related diseases such as acromegaly and gastrointestinal obstruction.
Public/Granted literature
- US20160311794A1 COMPOUND HAVING SOMATOSTATIN RECEPTOR AGONISTIC ACTIVITY AND PHARMACEUTICAL USE THEREOF Public/Granted day:2016-10-27
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