- Patent Title: 2-pyridyloxy-3-nitrile-4-substituted orexin receptor antagonists
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Application No.: US14653817Application Date: 2013-12-16
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Publication No.: US09643955B2Publication Date: 2017-05-09
- Inventor: Scott D. Kuduk , Jason W. Skudlarek
- Applicant: MERCK SHARP & DOHME CORP.
- Applicant Address: US NJ Rahway
- Assignee: MERCK SHARP & DOHME CORP.
- Current Assignee: MERCK SHARP & DOHME CORP.
- Current Assignee Address: US NJ Rahway
- Agent J. Eric Thies; John C. Todaro
- International Application: PCT/US2013/075236 WO 20131216
- International Announcement: WO2014/099698 WO 20140626
- Main IPC: C07D401/14
- IPC: C07D401/14 ; A61K31/4192 ; C07D413/00 ; C07D413/02
Abstract:
The present invention is directed to 2-pyridyloxy-3-nitrile-4-substituted compounds which are antagonists of orexin receptors. The present invention is also directed to uses of the 2-pyridyloxy-3-nitrile-4-substituted compounds described herein in the potential treatment or prevention of neurological and psychiatric disorders and diseases in which orexin receptors are involved. The present invention is also directed to pharmaceutical compositions comprising these compounds. The present invention is also directed to uses of these pharmaceutical compositions in the prevention or treatment of such diseases in which orexin receptors are involved.
Public/Granted literature
- US20150322041A1 2-PYRIDYLOXY-4-NITRILE-4-SUBSTITUTED OREXIN RECEPTOR ANTAGONISTS Public/Granted day:2015-11-12
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