Invention Grant
- Patent Title: Deprotection method for protected hydroxyl group
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Application No.: US14057384Application Date: 2013-10-18
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Publication No.: US09643958B2Publication Date: 2017-05-09
- Inventor: Yuichiro Ishibashi , Yasushi Matsumura
- Applicant: Asahi Glass Company, Limited
- Applicant Address: JP Chiyoda-ku
- Assignee: Asahi Glass Company, Limited
- Current Assignee: Asahi Glass Company, Limited
- Current Assignee Address: JP Chiyoda-ku
- Agency: Oblon, McClelland, Maier & Neustadt, L.L.P.
- Priority: JP2011-095211 20110421
- Main IPC: C07D405/06
- IPC: C07D405/06 ; C07B51/00 ; C07C29/10
Abstract:
To deprotect an alcoholic hydroxyl group protected by a t-butyldimethylsilyl group without influencing a functional group unstable to an acid. In the presence of a solvent, an alcohol having a hydroxyl group protected by a t-butyldimethylsilyl group is deprotected in the presence of an acid or an acid salt having a pKa of from 1.0 to 3.0 in water.
Public/Granted literature
- US20140058113A1 DEPROTECTION METHOD FOR PROTECTED HYDROXYL GROUP Public/Granted day:2014-02-27
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