Invention Grant
- Patent Title: Necroptosis inhibitors and methods of use therefor
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Application No.: US14004474Application Date: 2012-03-12
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Publication No.: US09643977B2Publication Date: 2017-05-09
- Inventor: Junying Yuan
- Applicant: Junying Yuan
- Applicant Address: US MA Cambridge
- Assignee: President and Fellows of Harvard College
- Current Assignee: President and Fellows of Harvard College
- Current Assignee Address: US MA Cambridge
- Agency: Choate, Hall & Stewart LLP
- Agent Brenda H. Jarrell; Nishat A. Shaikh
- International Application: PCT/US2012/028747 WO 20120312
- International Announcement: WO2012/125544 WO 20120920
- Main IPC: C07D403/06
- IPC: C07D403/06 ; C07D495/04 ; C07D417/12 ; C07D487/04 ; C07D209/82 ; C07D231/14 ; C07D231/40 ; C07D233/56 ; C07D235/30 ; C07D237/18 ; C07D409/06 ; C07D261/14 ; C07D263/58 ; C07D277/46 ; C07D277/54 ; C07C211/52 ; C07C235/38 ; C07D215/08 ; C07D261/20 ; C07D403/12 ; C07D405/06
Abstract:
Described herein are compositions that inhibit the production of TNFα downstream of CD40 activation. As such, also described are various methods of using compositions exhibiting this activity for the treatment or prevention of inflammatory diseases associated with TNFα production or CD40 activation.
Public/Granted literature
- US20140066466A1 Necroptosis Inhibitors and Methods of Use Therefor Public/Granted day:2014-03-06
Information query
