Invention Grant
- Patent Title: RTN4B polypeptide, monoclonal antibody thereof, monoclonal antibody-producing hybridoma cell strain, and, preparation and application thereof
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Application No.: US14397539Application Date: 2013-05-06
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Publication No.: US09644003B2Publication Date: 2017-05-09
- Inventor: Long Yu , Guoqing Ji , Dingding Han , Yanhua Wu , Lisha Tang
- Applicant: FUDAN UNIVERSITY
- Applicant Address: CN Yangpu District, Shanghai
- Assignee: FUDAN UNIVERSITY
- Current Assignee: FUDAN UNIVERSITY
- Current Assignee Address: CN Yangpu District, Shanghai
- Agency: Global IP Services
- Agent Tianhua Gu
- Priority: CN201210141101 20120508; CN201210171629 20120529
- International Application: PCT/CN2013/075184 WO 20130506
- International Announcement: WO2013/166943 WO 20131114
- Main IPC: C07K7/08
- IPC: C07K7/08 ; C07K14/47 ; C07K16/18 ; C12N5/16 ; G01N33/574 ; C07K16/22 ; A61K38/00 ; A61K39/00
Abstract:
The present invention relates to a RTN4B-related polypeptide, a monoclonal antibody thereof, a monoclonal antibody-producing hybridoma cell strain, and, preparation and applications thereof. The RTN4B polypeptide comprises an amino acid sequence presented by SEQ ID NO: 1. The invention further discloses a monoclonal antibody, a hybridoma cell strain to produce the monoclonal antibody prepared by the RTN4B polypeptide, and the related application in the treatment or prevention of tumors thereof.
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