Invention Grant
- Patent Title: Processes and recombinant microorganisms for the production of fine chemicals
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Application No.: US14365660Application Date: 2012-12-14
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Publication No.: US09644220B2Publication Date: 2017-05-09
- Inventor: Christoph Wittmann , Stefanie Kind , Judith Becker
- Applicant: BASF SE
- Applicant Address: DE Ludwigshafen
- Assignee: BASF SE
- Current Assignee: BASF SE
- Current Assignee Address: DE Ludwigshafen
- Agency: Marshall, Gerstein & Borun LLP
- Priority: EP11195301 20111222; EP12165935 20120427
- International Application: PCT/IB2012/057312 WO 20121214
- International Announcement: WO2013/093737 WO 20130627
- Main IPC: C12P13/08
- IPC: C12P13/08 ; C12P13/00 ; C12N9/00

Abstract:
Recombinant microorganisms with deregulated succinyl-CoA synthetase activity, as well as the uses for producing lysine, β-lysine, cadaverine or N-acetylcadaverine thereby are provided. Recombinant polypeptides comprising an amino acid sequence being at least 80% identical to SEQ ID NO: 51 or 53 are also provided. The method of producing fine chemicals using said recombinant microorganisms, in particular the method of producing lysine, or derivatives thereof, such as β-lysine, cadaverine or N-acetylcadaverine is further provided.
Public/Granted literature
- US20140356916A1 PROCESSES AND RECOMBINANT MICROORGANISMS FOR THE PRODUCTION OF FINE CHEMICALS Public/Granted day:2014-12-04
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