Invention Grant
- Patent Title: Genetic factors associated with inhibitor development in hemophilia A
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Application No.: US13207286Application Date: 2011-08-10
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Publication No.: US09644239B2Publication Date: 2017-05-09
- Inventor: Jan Astermark , Erik Berntorp
- Applicant: Jan Astermark , Erik Berntorp
- Applicant Address: SE Malmö SE Malmö
- Assignee: Jan Astermark,Erik Berntorp
- Current Assignee: Jan Astermark,Erik Berntorp
- Current Assignee Address: SE Malmö SE Malmö
- Agency: Morgan, Lewis & Bockius LLP
- Main IPC: C40B30/04
- IPC: C40B30/04 ; C12Q1/68
Abstract:
The present invention provides methods for predicting the risk of an individual developing antibodies to factor VIII by identifying a single nucleotide polymorphism of an immune response or immune modifier gene. The invention further provides oligonucleotides, diagnostic kits, microarrays, and isolated nucleic acids comprising single nucleotide polymorphisms of immune response or immune modifier genes.
Public/Granted literature
- US20120065077A1 GENETIC FACTORS ASSOCIATED WITH INHIBITOR DEVELOPMENT IN HEMOPHILIA A Public/Granted day:2012-03-15
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