An intelligent virtual desktop infrastructure (iVDI) system is described. The system includes a first storage module having a processor, in communication with a hypervisor, and implemented by a volatile memory. The first storage module supplies a plurality of virtual machine operating systems (VMOSs) to the hypervisor. The hypervisor runs virtual machine (VMs) corresponding to the VMOSs. The systems also includes a VMOS management module configured to execute a first determination operation to determine if a usage of the first storage module has reached a preset storage limit. If yes, the VMOS management module selectively (a) initiate a deduplication operation directed to the plurality of VMOSs stored in the first storage module and (b) initiate a removal operation including removing at least one of the VMOSs from the first storage module and/or turning off at least one of the VMs running on the hypervisor.