Concepts and technologies are disclosed herein for managing resource access in distributed computing environments. A computing device can host a local resource such as a file or application and an application for managing or controlling resource access. The user device can communicate with a remote device that hosts a remote resource, which may be similar to the local resource. If a resource access request is detected at the user device, the user device can identify resources including a local resource and/or a remote resource that can provide functionality associated with the request. The user device can determine if the local resource, the remote resource, and/or a combination thereof is to be accessed to provide the requested access. This determination can be made before or during the access and can be based upon settings, preferences, input, network traffic, and/or other considerations determined at the user device and/or other devices.