A method and apparatus for physically secure communication over machine-to-machine (M2M) networks is claimed, through the use of frequency-hop and random access spread spectrum modulation formats employing using truly random spreading codes and time/frequency hopping and receiver selection strategies at the transmitters in the M2M network, blind signal detection and linear signal separation techniques at the receivers in the M2M network, completely eliminating the ability for an adversary to predict and override M2M transmissions. Additional physical security protocols are also introduced that allow the network to easily detect and identify spoofing transmissions on uplinks and downlinks, and to automatically excise those transmissions as part of the despreading procedure, even if those transmissions are received at a much higher power level than the intended transmissions. Extensions to weakly and strongly macrodiverse networks are also described, which provide additional efficiency and security improvements by exploiting the route diversity of the network.