Provided is a control device for an internal combustion engine, which is capable of suppressing occurrence of knocking due to pre-ignition and occurrence of misfire even when an operating state in a previous cycle changes in a subsequent cycle. When a ratio of change in heat of air-fuel mixture, which is an index indicating how a heat of air-fuel mixture in the previous cycle changes in the subsequent cycle, does not fall within an allowable range, a variable valve control mechanism capable of changing a valve-closing timing of an exhaust valve for adjusting an internal EGR gas amount is controlled by using an optimum value of exhaust valve close (EVC) timing derived by correcting a set valve-closing timing of the exhaust valve so that the ratio of change in heat of air-fuel mixture falls within the allowable range.