The subject matter described herein relates to application installation/uninstallation across multiple systems. Responsive to installation or uninstallation of an application on a first system running on a device, it is determined whether the application is to be installed or uninstalled on a second system. Responsive to determining that the application is to be installed or uninstalled on the second system, an indication is set while the first system is running, where the indication causes installation or uninstallation of the application on the second system.