Embodiments relate to load queue entry reuse for operand store compare (OSC) history table update. An aspect includes allocating a load queue entry in a load queue to a load instruction that is issued into an instruction pipeline, the load queue entry comprising a valid tag that is set and a keep tag that is unset. Another aspect includes based on the flushing of the load instruction, unsetting the valid tag and setting the keep tag. Another aspect includes reissuing the load instruction into the instruction pipeline. Another aspect includes based on determining that the allocated load queue entry corresponds to the reissued load instruction, setting the valid tag and leaving the keep tag set. Another aspect includes based on completing the reissued load instruction, and based on the valid tag and the keep tag being set, updating the OSC history table corresponding to the load instruction.