Invention Grant
- Patent Title: Treatment of sickle cell disease
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Application No.: US14345206Application Date: 2012-09-13
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Publication No.: US09655905B2Publication Date: 2017-05-23
- Inventor: Magbubah Essack , Vladimir Bajic , Aleksandar Radovanovic
- Applicant: Magbubah Essack , Vladimir Bajic , Aleksandar Radovanovic
- Applicant Address: SA Thuwal
- Assignee: KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY
- Current Assignee: KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY
- Current Assignee Address: SA Thuwal
- Agency: Smith, Gambrell & Russell, LLP
- International Application: PCT/IB2012/002887 WO 20120913
- International Announcement: WO2013/057592 WO 20130425
- Main IPC: A61K31/00
- IPC: A61K31/00 ; A61K31/47 ; A61K31/551 ; A61K31/341 ; A61K45/06 ; A61K31/365 ; A61K31/55 ; A61K31/472
Abstract:
The present invention includes embodiments for treatment and/or prevention of sickle cell disease that employ Hydroxyfasudil or Isocoronarin D alone or either in conjunction with each other or an inducer of HbF production. The compounds may act synergistically, and the compounds employed circumvent the side effects seen with Hydroxyurea.
Public/Granted literature
- US20140356458A1 TREATMENT OF SICKLE CELL DISEASE Public/Granted day:2014-12-04
Information query
