Invention Grant
- Patent Title: Adenylate cyclase deficient bordetella strains
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Application No.: US14870487Application Date: 2015-09-30
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Publication No.: US09655959B2Publication Date: 2017-05-23
- Inventor: Sylvie Claudette Alonso , Rui Fen Annabelle Lim , Camille Locht
- Applicant: National University of Singapore , Institut Pasteur de Lille , Institut National de la Santé et de la Recherche Médicale (INSERM)
- Applicant Address: SG Singapore FR Paris FR Lille
- Assignee: National University of Singapore,Institut National de la Santé et de la Recherche Médicale (INSERM),Institut Pasteur de Lille
- Current Assignee: National University of Singapore,Institut National de la Santé et de la Recherche Médicale (INSERM),Institut Pasteur de Lille
- Current Assignee Address: SG Singapore FR Paris FR Lille
- Agent Stanley A. Kim
- Main IPC: A61K39/02
- IPC: A61K39/02 ; A61K39/00
Abstract:
A CyaA-deficient B. pertussis mutant was constructed and used in a vaccine. The pertussis-specific antibody profile and Th17 response induced by vaccination with the mutant was surprisingly comparable to that induced by B. pertussis strains not deficient in CyaA.
Public/Granted literature
- US20160095914A1 Adenylate Cyclase Deficient Bordetella Strains Public/Granted day:2016-04-07
Information query
