A hand tool frame has a track base, a positioning board, and at least one positioning mount. The track base has a bottom panel and a slide rail. The positioning board is mounted in the track base and has multiple engaging holes formed through the positioning board. The at least one positioning mount is slidably mounted on the track base and has a sliding seat and an extending element. The sliding seat is slidably mounted in the slide rail and has a body, a positioning portion, and an engaging protrusion. The engaging protrusion is formed on and protrudes from the positioning portion, and selectively engages with one of the engaging holes to enable the sliding seat to securely mount on the positioning board without sliding relative to the track base. The extending element is formed on and protrudes from the sliding seat.