Invention Grant
- Patent Title: Ring-contracted morphinans and the use thereof
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Application No.: US15108091Application Date: 2014-12-19
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Publication No.: US09656962B2Publication Date: 2017-05-23
- Inventor: Jeffrey Lockman , Laykea Tafesse
- Applicant: Purdue Pharma L.P.
- Applicant Address: US CT Stamford
- Assignee: Purdue Pharma L.P.
- Current Assignee: Purdue Pharma L.P.
- Current Assignee Address: US CT Stamford
- Agency: Purdue Pharma L.P.
- Agent Alan L. Koller; Weiyung Yang
- International Application: PCT/US2014/071605 WO 20141219
- International Announcement: WO2015/100174 WO 20150702
- Main IPC: C07D221/22
- IPC: C07D221/22 ; A61K31/4748 ; C07D221/28
Abstract:
The application is directed to compounds of Formula (I) or (IA) and pharmaceutically acceptable salts and solvates thereof, wherein R1 R2, R3 and G are defined as set forth in the specification. The invention is also directed to use of compounds of Formula (I) or (IA), and the pharmaceutically acceptable salts and solvates thereof, to treat disorders responsive to the modulation of one or more opioid receptors, or as synthetic intermediates. Certain compounds of the present invention are especially useful for treating pain.
Public/Granted literature
- US20160340316A1 RING-CONTRACTED MORPHINANS AND THE USE THEREOF Public/Granted day:2016-11-24
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