Invention Grant
- Patent Title: ENA nucleic acid pharmaceuticals capable of modifying splicing of mRNA precursors
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Application No.: US13673466Application Date: 2012-11-09
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Publication No.: US09657049B2Publication Date: 2017-05-23
- Inventor: Masafumi Matsuo , Yasuhiro Takeshima , Makoto Koizumi
- Applicant: Masafumi Matsuo , Yasuhiro Takeshima , Makoto Koizumi
- Applicant Address: JP Kobe-shi JP Nishinomiya JP Tokyo JP Tokyo
- Assignee: Masafumi Matsuo,Yasuhiro Takeshima,Orphan Disease Treatment Institute Co., Ltd.,Daiichi Sankyo Company, Limited
- Current Assignee: Masafumi Matsuo,Yasuhiro Takeshima,Orphan Disease Treatment Institute Co., Ltd.,Daiichi Sankyo Company, Limited
- Current Assignee Address: JP Kobe-shi JP Nishinomiya JP Tokyo JP Tokyo
- Agency: Oblon, McClelland, Maier & Neustadt, L.L.P.
- Priority: JP2002-340857 20021125; JP2003-204381 20030731
- Main IPC: C12N15/113
- IPC: C12N15/113 ; C07H21/02 ; C07H21/04 ; A61K38/00 ; A61K48/00
Abstract:
Oligonucleotides having a nucleotide sequence complementary to nucleotide numbers such as 2571-2607, 2578-2592, 2571-2592, 2573-2592, 2578-2596, 2578-2601 or 2575-2592 of the dystrophin cDNA (Gene Bank accession No. NM_004006.1) and therapeutic agents for muscular dystrophy comprising such oligonucleotides.
Public/Granted literature
- US20130090465A1 ENA NUCLEIC ACID PHARMACEUTICALS CAPABLE OF MODIFYING SPLICING OF mRNA PRECURSORS Public/Granted day:2013-04-11
Information query
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